Side effects associated with use of OxyContin are constipation, nausea, sedation, dizziness, vomiting, headache, dry mouth, sweating, mood changes, flushing, loss of appetite, and weakness.
Nasal decongestants including Afrin and Otrivin can cause rebound congestion as part of withdrawal from these medications if used for more than a few days.
Methamphetamine produces more extensive and pronounced effects on the brain and central nervous system than cocaine or amphetamine.
Methadone has an extremely high risk of physical dependence, and when not taken daily users will experience very painful withdrawal symptoms.