Morphine withdrawal symptoms can last for up to 10 days, while withdrawal from methadone may take weeks or months.
The largest increases in prescription drug related emergency room visits between 2004 and 2009 were for oxycodone products (242.2 percent increase), alprazolam (148.3 percent increase), and hydrocodone products (124.5 percent).
Although the euphoric effects of cocaine on the user dissipate within minutes or hours of use, the "come down" or cocaine withdrawal can be felt for much longer.
The psychological dependence commonly associated with Opana addiction can persist well beyond the typical physical withdrawal period.