Undesirable psychological effects caused by Ecstasy use can include loss of appetite, fatigue, confusion, sleep disturbances, anxiety, paranoia and even psychotic episodes.
The heroin found in the U.S. is produced in four distinct geographical areas: South America (Colombia), Southeast Asia (primarily Burma), Mexico, and Southwest Asia (principally Afghanistan).
Rates of death as a result of motor vehicle crashes and alcoholism are 5.5 and 3.8 times higher, respectively, for American Indians than among the general population.
Taking magic mushrooms with certain MAOI drugs can dramatically increase the effects of the experience.