The morning after an alcohol binge, the body's organs try to make up for their own water loss by taking it from the brain causing the brain to decrease in size and pull on the membranes that connect the brain to the skull, resulting in pain.
Repeated, heavy use of crack cocaine will eventually lead to decreased sexual desire, which may lead to total abstinence from sex. Impotence in males is also possible.
Opiate withdrawal symptoms are stronger approximately 24-72 hours after they begin and generally dissipate within 7-10 days.
While abuse of OxyContin was once seen as a "white-collar" addiction, this problem has been on the rise among all ethnic and economic groups.